The Restylane Treatment Plan involves an initial treatment with Restylane injectable gel and two follow-up treatments at 4.5 or 9 months, and 18 months later. On average, only half the amount of Restylane used at the initial treatment is needed to achieve full correction at the follow-up treatments. In a clinical study treating the lines from the nose to the corner of the mouth (laugh lines), at least 94% of patients treated with Restylane injectable gel maintained results for up to 3 years1* when they followed the Restylane Treatment Plan. Full Correction and the Restylane Treatment Plan1 The Restylane Treatment Plan may help maintain full correction results for up to 36 months. Your doctor may recommend a Restylane Treatment Plan tailored to your specific needs.